WebApr 23, 2014 · The discovery of stem and progenitor cells in the adult mammalian heart has added a vital dimension to the field of cardiac regeneration. Cardiac-resident stem cells are likely sequestered as reserve cells within myocardial niches during the course of embryonic cardiogenesis, although they may also be recruited from external sources, such as bone … WebOf particular interest following all results presented above is the similarity between PC95, a mutant of the replicase NIb gene, and CLA11, a mutant of the VSR HC-Pro gene. These two mutations led to close fitness values ( Fig. 2A) , but also resulted in significantly similar gene expression profiles (Fig. 4B ).
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WebApr 26, 2024 · Such strategies may be ill-suited to map gene expression in developing embryos, which exhibit dramatically increasing cell-state dimensionality and continuous changes in the sets and numbers of cell state–defining genes (fig. S2, D and E). ... Highly canalized regions of the graph correspond to branches with the fewest off-tree edges. … WebSimilar genotypic changes may result in similar phenotypic alterations, even across a wide range of species. [1] The genotype–phenotype distinction is drawn in genetics. "Genotype" is an organism's full hereditary information. "Phenotype" is an organism's actual observed properties, such as morphology, development, or behavior. pho winnipeg
Genotype–phenotype distinction - Wikipedia
WebFeb 26, 2015 · At stressful conditions, this canalized gene expression is disturbed resulting in many significant differences between the two parental strains as well as significant cis-and trans-effects. Following the widely accepted hypothesis that canalization of traits is the consequence of stabilizing selection (reviewed in [ 3 , 4 ]), our data suggest ... Ultralow-input transcriptome sequencing was performed for individual samples of two ant species, M. pharaonis and A. echinatior (both subfamily Myrmicinae), covering four larval stages, the prepupal stage, the early and late pupal stage and the adult stage (Extended Data Table 1). Individual transcriptomes were also … See more RNA quality testing, production of complementary DNA libraries and sequencing were performed at BGI, China. The quality of RNA samples was tested with Agilent 2100 … See more Heads, thoraxes and gasters (fourth and higher abdominal segments) were dissected from newly eclosed gynes and gasters were subdivided by tissue into digestive glands, … See more Third instar reproductive (gyne or male) larvae were taken from nests and fixed with double-sided adhesive tapes. Interference double-strand RNA (dsRNA) was then injected into the upper ventral abdomen with a … See more WebWe observe that natural selection acts to preserve canalized gene expression in populations of killifish that are most tolerant to abrupt salinity change a nd that these populations show the least variability in their transcription of genes enabling plasticity of the gill. We fo und that genes participating in this highly canalized and pho winnipeg menu