WebAll of this may be done in the presence of covariates (such as sex, age or treatment). One may also fit higher-order QTL models by multiple imputation and Haley-Knott regression. R/qtl is distributed as source code for unix or compiled code for Windows or Mac. R/qtl is released under the GNU General Public License. To download the software, you ... WebFeb 5, 2024 · We have currently focused solely on Haley-Knott regression (Haley and Knott 1992) for QTL analysis. This has a big advantage in terms of computational speed, but it …
Genetic regression function - RDocumentation
WebMar 26, 2024 · Details. For each of the inputs, the row names are used as individual identifiers, to align individuals. If kinship is absent, Haley-Knott regression is performed. If kinship is provided, a linear mixed model is used, with a polygenic effect estimated under the null hypothesis of no (major) QTL, and then taken as fixed as known in the genome … WebJun 14, 2014 · We fi rst applied interval mapping by Haley – Knott regression (Haley and Knott 1992), considering each time point indi-vidually. The results are displayed in Fi gure 1, with th e x-axis. pmfr wheels
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WebSep 17, 2010 · We used the implementation of Haley-Knott regression available in the qtl package for R. LOD scores were calculated at the marker locations. Composite interval mapping To perform composite interval mapping [ 19 ] we used the implementation in the qtl package for R, with the method argument set to "EM", and all other arguments set to … WebOct 1, 1992 · Haley, C., Knott, S. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69, 315–324 (1992). … WebThe Haley–Knott (HK) regression method applied to backcross data consists simply of regressing the individuals' phenotypes on the conditional probabilities for having … pmfs consulting